Results 71 to 80 of about 2,470,978 (359)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Petitions by medical practitioners 1632-1732 [PDF]

open access: yes, 2006
The very humble suppliche or petitions addressed by subjects to the Grand Masters constitute a major source of information about everyday life in Malta at the time of the knights.
Bonello, Giovanni
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Registers of births as a source on the history of settlements.

open access: yesИсторическая этнология, 2019
The study of the history of human settlements in recent decades has become very popular. Not just professional historians, but also fans of history show interest in this problem.
Elmira K. Salakhova
doaj   +1 more source

Distilling Information Reliability and Source Trustworthiness from Digital Traces

open access: yes, 2017
Online knowledge repositories typically rely on their users or dedicated editors to evaluate the reliability of their content. These evaluations can be viewed as noisy measurements of both information reliability and information source trustworthiness ...
Aalen O.   +15 more
core   +1 more source

THE PORTRAYAL OF ANDREJ HLINKA IN SLOVAK HISTORIOGRAPHY [PDF]

open access: yes, 2016
Th e paper analyzes the course of the process of historical research of the personality of Andrej Hlinka. One of the most signifi cant fi gures of the Slovak history in general became the subject of interest of the Slovak historians only gradually ...
Letz, Róbert
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The Disingenuousness of the Jesus Legend in Popular Media [PDF]

open access: yes, 2016
In America today, a major source of contention among theologians involves the Resurrection, a controversy that has ensued since historical times (1 Cor 15: 12-19 [KJV]).
Louie, Emma L
core   +1 more source

Estimating trends in the global mean temperature record [PDF]

open access: yes, 2017
Given uncertainties in physical theory and numerical climate simulations, the historical temperature record is often used as a source of empirical information about climate change.
Moyer, Elisabeth J.   +2 more
core   +3 more sources

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