Results 61 to 70 of about 334,606 (308)

The Manufacture of Lake Pigments from Artificial Colours: Investigating Chemistry and Recipes in the First Book on Synthetic Dyes-Based Lakes

open access: yesHeritage
In 1900, Francis Herbert Jennison’s book The Manufacture of Lake Pigments from Artificial Colours was published in London. In the early 20th century, the technical literature focussing on synthetic dyes mainly dealt with their use for dyeing. Conversely,
Eva Eis   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Undergraduate L2 students’ performance when evaluating historical sources for reliability [PDF]

open access: yes, 2021
Evaluating historical sources for reliability, an aspect of sourcing, is a key feature of historical reasoning. While well-studied among proficient and L1 students, the performance of L2 students and the role of their English proficiency is not as well ...
Van Boxtel, Carla   +5 more
core   +1 more source

Oral History as a Selection of Sources: Discussion Around "'O tym nie wolno mówić…' Zagłada Żydów w opowieściach wspomnieniowych ze zbiorów Dionizjusza Czubali" ['We Are Not Allowed to Speak About It...' The Extermination of Jews in Memoirs from the Collection of Dionizjusz Czubala]

open access: yesStudia Litteraria et Historica, 2020
This article reviews the book „O tym nie wolno mówić…” Zagłada Żydów w opowieściach wspomnieniowych ze zbiorów Dionizjusza Czubali [“We Are Not Allowed to Speak About It...” The Extermination of Jews in Memoirs from the Collection of Dionizjusz Czubala],
Piotr Filipkowski
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

O “direito à memória”: Escola Eunice Weaver, memória individual e a constituição de um arquivo histórico em Goiás

open access: yesHistória, Ciências, Saúde: Manguinhos
Resumo Apresenta-se a constituição do arquivo documental da Escola Eunice Weaver, parte do complexo formador do Educandário/Preventório Afrânio de Azevedo, inaugurado em 1943, em Goiânia. Destaca a importância da constituição de arquivos como esse para o
Leicy Francisca da Silva   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Teacher training on application of historical method in teaching and professional development [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2017
Contemporary teaching of social sciences has a goal of transferring selected knowledge to students with as much of their active participation in the process of teaching as possible, primarily, through student activity while working with documents and ...
Deletić Zdravko M.   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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