Results 191 to 200 of about 12,078,524 (337)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Editorial: Parasites of freshwater fish: diversity, invasions, pathologies, and zoonoses. [PDF]

Front Vet Sci
Viozzi G, Rauque C, Riscala Madi R.
europepmc   +1 more source

A Specific-Factors Model with Historical Application.

, 2016
In 1971, Ronald Jones examined a three-factor two-good model under the assumption that two of the factors are specific to one sector (a different sector for each such factor). Working independently, in the same year Paul Samuelson developed a similar framework.
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

In Situ Analysis of Historical Preservation Fluids in Sealed Containers with Spatially Offset Raman Spectroscopy. [PDF]

ACS Omega
Blanco A, Montgomery W, Walker S, McKibbin C, Stokes R, Matousek P, Mosca S.   +6 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

The Forgotten History of Bacteriophages in Bulgaria: An Overview and Molecular Perspective on Their Role in Addressing Antibiotic Resistance and Therapy. [PDF]

Viruses
Kalvatchev N, Khanbabapour T, Sakkeer A, Tsekov I, Delchev Y, Strateva T.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Diagnostic accuracy, fairness and clinical implementation of AI for breast cancer screening: results of multicenter retrospective and prospective technical feasibility studies. [PDF]

Nat Cancer
Kelly CJ, Wilson M, Warren LM, Sidebottom R, Halling-Brown M, Yang L, Morigami M, Venton J, Chopra R, Chang J, Dixon J, Gilbert FJ, Golden DI, Gruzewska E, Honeyfield L, Hujan A, Khodabakhshi D, Lewis E, Malhotra N, Mallya R, Ogunleye D, Purdy C, Sayres R, Sieniek M, Stoycheva T, Sy A, Thomas S, Ward D, Xi L, Xu S, Shetty S, Darzi A, Young K, Purushothaman H, Khoo L, Reddy M, Ashrafian H, Cunningham D.   +37 more
europepmc   +1 more source

The Pedigrees of Rights and Powers in Scalia\u27s Cruzan Concurrence [PDF]

, 1994
Zipursky, Benjamin C.
core   +1 more source