Results 41 to 50 of about 835,368 (300)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
User Collaboration for Improving Access to Historical Texts
The paper will describe how web-based collaboration tools can engage users in the building of historical printed text resources created by mass digitisation projects.
Clemens Neudecker, Asaf Tzadok
doaj +1 more source
Early Carthusian Script and Silence [PDF]
At its founding and during its first three decades, the Carthusian order developed a distinctive and forceful concept of communication among the members and between the members and the extramural world.2 Saint Bruno’s life ...
Gilbert, Bennett
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Examining trends in epidemic typhus using historical texts
Background & objectives: Although associated with conflict, epidemic typhus was endemic across Europe into the modem period. The extent of the problem it caused is uncertain as record keeping in the most affected socioeconomic groups was rare.
Mark David Walker
doaj +1 more source
How Does Science Come to Speak in the Courts? Citations Intertexts, Expert Witnesses, Consequential Facts, and Reasoning [PDF]
Citations, in their highly conventionalized forms, visibly indicate each texts explicit use of the prior literature that embodies the knowledge and contentions of its field.
Bazerman, Charles
core +1 more source
Digital Presentation of Bulgarian Lexical Heritage. Towards an Electronic Historical Dictionary [PDF]
The article presents the results of the project “ICT Tools for Historical Linguistic Studies”, funded by the European Social Fund, OP Human Resources.
Totomanova, Anna-Maria
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Interpreting and Explaining Historical Texts – Is it Possible?
With reference to particular problems of interpretations that radio listeners of today are likely to encounter when listening to a Norwegian radio reportage from the 1930s, this article discusses the question of whether it is possible for present-day ...
Vagle Wenche
doaj +1 more source
Reading Matthew as a historical narrative
The grammatico-historical method of Bible interpretation is often used in traditional reformed hermeneutics and is usually defined as distinctive from historical and reader-response criticism.
Francois P. Viljoen
doaj +1 more source

