The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Fully automated sequence alignment methods are comparable to, and much faster than, traditional methods in large data sets: an example with hepatitis B virus [PDF]
Aligning sequences for phylogenetic analysis (multiple sequence alignment; MSA) is an important, but increasingly computationally expensive step with the recent surge in DNA sequence data.
Therese A. Catanach+10 more
doaj +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Primary molt in Gruiforms and simpler molt summary tables [PDF]
Molt summary tables reveal the sequence and mode of flight-feather replacement and how these feathers are divided into independent replacement series. Tables for summarizing molt are relatively new, and the rules for generating them were first formally ...
Sievert Rohwer, Vanya G. Rohwer
doaj +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
University Scholar Series: Scott Myers-Lipton [PDF]
Rebuild America: Solving the Economic Crisis through Civic Works On October 13, 2010, Scott Myers-Lipton spoke in the University Scholar Series hosted by Provost Gerry Selter at the Dr. Martin Luther King, Jr. Library.
Myers-Lipton, Scott
core +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Breeding and multiple waves of primary molt in common ground doves of coastal Sinaloa [PDF]
For adult Common Ground Doves from Sinaloa we demonstrate that the primaries are a single molt series, which sometimes feature two (in one case three) waves of feather replacement. Such stepwise primary replacement is found in many large birds but, at 40
Sievert Rohwer, Vanya G. Rohwer
doaj +2 more sources
Child Labor in America: History, Policy, and Legislative Issues [PDF]
[Excerpt] This report examines the historical issue of child labor in America and carries it through the 108th ...
Whittaker, William G.
core +2 more sources
How green was my valley? Urban history in Latin America [PDF]
The history of Latin America has been dominated by ideas of order and progress. Unfortunately those ideas have not always been of regional origin. In the colonial era the conquest and conversion of the native peoples was seen as progress by the Europeans.
Derham, Michael
core +1 more source