Results 81 to 90 of about 560,734 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Emergence of Modern America 1865-Present
, 2018 This subject studies the changing structure of American politics, economics, and society from the end of the Civil War to the present. We will consider secondary historical accounts and primary documents to examine some of the key issues in the ...
Faculty, History Department
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
1975 Miss Wheelchair America Pageant awards stage
, 1974 This photograph shows the empty auditorium and awards stage for the 1974-75 Miss Wheelchair America ...
Miss Wheelchair America Pageant.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Bev Chapman's Miss Wheelchair America van
, 1977 A photograph of the Miss Wheelchair America van with "Bev Chapman Miss Wheel Chair 1977" written on the ...
Miss Wheelchair America Pageant.
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Impact of the NeighborWorks America Catalytic Grant Program [PDF]
, 2017 Over an 18-month period, NeighborWorks America ran a program through its Community Initiative Department called the Catalytic Grant Program (CGP).CGP was inspired by Community Initiatives' mission to support efforts to build vibrant local communities ...
NeighborWorks America
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
1980 Miss Wheelchair America Pageant program
, 1980 Front cover of the Miss Wheelchair America Pageant 1980 program, including the MWA logo printed in the center and "Eighth Annual Pageant 1980" printed ...
Miss Wheelchair America Pageant.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source