Results 101 to 110 of about 10,380,327 (309)

Common Law, History, and Democracy in America, 1790-1900: Legal Thought Before Modernism

, 2011
This book argues for a change in our understanding of the relationships among law, politics and history. Since the turn of the nineteenth century, a certain anti-foundational conception of history has served to undermine law\u27s foundations, such that ...
Parker, Kunal, Parker, Kunal M.
core   +1 more source

Remembering Michael Ruse

Journal of Interdisciplinary Ethical Research
No Abstract ...
Jane Maienschein, Vassiliki B. Smocovitis   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

1976 Miss Wheelchair America Pageant brochure

, 1975
Informational pamphlet for the 1976 MWA Pageant, including information and history, biographies of past winners, and mailing information for potential donors or ...
Miss Wheelchair America Pageant.
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

History of the Michigan Conference, Wesleyan Methodist Church of America,

, 1940
"History of the Woman's home and foreign missionary society, Michigan conference, Wesleyan Methodist church of America, 1890-1940 [by] Mrs. Mabel Perrine": 121 p. at end.Issued with Mrs.
Rennells, Charles S. (Charles Stephen), 1873-1962., Perrine, Mabel, Mrs. History of the Woman's home and foreign missionary society, Michigan conference, Wesleyan Methodist Church of America.   +1 more
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Influence Of Mediation Factors Between Entrepreneurship Education And Entrepreneurial Intentions: A Systematic Literature Review

Journal of Economic Education
Entrepreneurship education is designed to improve knowledge, skills, and an entrepreneurial mindset. However, the impact on entrepreneurial interest is not always direct, but is influenced by factors that mediate the relationship between entrepreneurial
Rusdiaman Rauf, Eric Alan Jones
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source