Results 111 to 120 of about 10,380,327 (309)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Annual Report of the Boy Scouts of America

open access: yes, 1936
Monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Annual Report of the Boy Scouts of America

open access: yes, 1933
Monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Margie Sloan portrait

open access: yes, 1977
Margie Sloan, with crown and flowers, poses under the Miss Wheelchair America ...
Miss Wheelchair America Pageant.
core  

The other Europeans : inmigration into Latin America and the international labour market (1870-1930) [PDF]

open access: yes, 2007
Not all Europeans migrated to the United States. Between 1879 and 1930 13 million of Europeans went to Latin America; however, Latin America is not fully incorporated into current debates on the cost and benefits from Atlantic migration.
Sánchez-Alonso, Blanca
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The myth of “pre-history”: the pre-contact history of indigenous North America [PDF]

open access: yes
From its “discovery,” North America has been considered terra nullius, empty land ripe for cultivation and settlement. This conceptualization has infected the historical imagination, relegating the history of North America before the arrival of Europeans
Henson, Isra
core  

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