Results 111 to 120 of about 560,734 (316)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 1977 Margie Sloan, with crown and flowers, poses under the Miss Wheelchair America ...
Miss Wheelchair America Pageant.
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FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
, 1976 Carol Sue Cyrus, Miss Wheelchair Ohio, smiles in the 1976-77 Miss Wheelchair America Pageant. The Miss Wheelchair America Pageant was founded in September, 1971, by an Ohio psychiatrist who wished to establish a spokesperson for disabled Americans.
Miss Wheelchair America Pageant.
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Growth, inequality, and poverty in Latin America: historical evidence, controlled conjectures. [PDF]
, 2005 How have growth and inequality affected poverty reduction in Latin America over the long run? On the basis of the available evidence on growth and inequality tentative answers and conjectures are proposed about the long run evolution of poverty in Latin ...
Prados de la Escosura, Leandro
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Common Law, History, and Democracy in America, 1790-1900: Legal Thought Before Modernism
, 2011 This book argues for a change in our understanding of the relationships among law, politics and history. Since the turn of the nineteenth century, a certain anti-foundational conception of history has served to undermine law\u27s foundations, such that ...
Parker, Kunal, Parker, Kunal M.
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Annual Report of the Boy Scouts of America
, 1941 Monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
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