Results 121 to 130 of about 560,734 (316)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Annual Report of the Boy Scouts of America

open access: yes, 1936
Monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Annual Report of the Boy Scouts of America

open access: yes, 1933
Monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Fifth Annual Report of the Boy Scouts of America

open access: yes, 1915
Semi-monthly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns ...
Boy Scouts of America
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Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Contestants relaxing poolside

open access: yes, 1973
Five Miss Wheelchair America contestants smiling and sitting in their wheelchairs beside a swimming ...
Miss Wheelchair America Pageant.
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Miss Wheelchair America participant enjoys ice cream

open access: yes, 1976
A participant in the 1976-77 MWA Pageant is excited to receive her cup of ice ...
Miss Wheelchair America Pageant.
core  

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