Results 81 to 90 of about 2,745,921 (358)
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Using History to Study Information Seeking Behavior [PDF]
, 2010 has focused on approaches that provide a snapshot in time of what is going on in a household. This poster explores the use of history to examine changes over time in both information questions and information sources used in the prosecution of ...
Aspray, William, Hayes, Barbara
core
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
UNASUR: Developments in the Defense Area [PDF]
, 2013 The article summarizes the last developments in South America towards a common defense area, referring to the history and origins of the Union of South American Nations (UNASUR).Fil: Gil, Luciana Victoria. Universidad de Buenos Aires; Argentina.
Gil, Luciana Victoria
core
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
America in ‘British’ history textbooks
, 2018 Always far more special in London than in Washington, the so-called Anglo-American (a.k.a. UK-US) special relationship has greatly influenced British foreign policy for at least seven decades, and it continues to influence it under the conditions of ‘Brexit’ and the radical presidency of US President Donald Trump.
openaire +4 more sources
The Latin American Consensus [PDF]
, 2007 Anti-Americanism has reached an unsettling global high that has been manifested in everything from opinion polls to violent protests. Latin America is geopolitically important to the United States, while harboring anti-American sentiment.
Miralrio, Amanda
core +2 more sources
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source