Results 81 to 90 of about 9,940,766 (374)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Ghosts from the past: a review of fossil Hepialoidea (Lepidoptera) [PDF]

open access: yesPeerJ, 2019
We critically re-examine nine of the ten fossil specimens currently assigned to Hepialidae. Three fossils with impressions of wing veins and scales placed in the fossil genus Prohepialus Piton, 1940, and two mummified larvae that show apomorphic ...
Thomas J. Simonsen   +2 more
doaj   +2 more sources

Book Reviews [PDF]

open access: yes, 1999
M. P. Marcelli & T. Ahti (eds.) 1998. Recollecting Edvard August Vainio. CETESB, Sao Paulo, 188 pp (A5). Price US$ 30.00 + postage US$ 14.00 = US$ 44.00. M. P. Marcelli & M. R. D. Seaward (eds.) 1998.
Aptroot, André
core  

Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals

open access: yesPLoS Genetics, 2014
The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification.
A. Ruiz-Linares   +33 more
semanticscholar   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

[Review of] John Higham (Ed.), Ethnic Leadership in America [PDF]

open access: yes, 1979
The growing awareness of America\u27s ethnic pluralism has become one of the factors shaping modern American history. Ethnic writers, as well as ethnic leaders, began the task of illuminating the meaning of their own historic and cultural traditions ...
Blicksilver, Edith
core   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Review of \u3cem\u3eThe Loyal West: Civil War and Reunion in Middle America\u3c/em\u3e by Matthew E. Stanley [PDF]

open access: yes, 2018
Interest in Civil War memory and post–Civil War sectional reconciliation has expanded greatly in recent years, as two 2016 historiographical essays attest.1 Matthew E. Stanley\u27s new book, The Loyal West: Civil War and Reunion in Middle America is thus
Harris, M. Keith   +4 more
core   +1 more source

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