Results 121 to 130 of about 16,191,908 (309)

Uses of History in History Education

open access: yes, 2016
This compilation thesis contains an introductory chapter and four original articles. The studies comprising this thesis all concern aspects of how historical culture is constituted in historical media and history teachers’ narratives and teaching. It is argued that the teaching of history is a complex matter due to an internal tension resulting from ...
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Oral History Theater for Young People: Old Wives’ Tales?

open access: yesSocieties
This paper presents findings from an oral history theater project, developed by older individuals, aimed at primary and secondary school students. A professional theater company in Hong Kong has completed a three-year initiative that recruited retired ...
Jack Shu
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Arts education : validation draft

open access: yes, 2000
Arts Education - Validation Draft February ...
Atlantic Provinces Education Foundation
core  

Differentiated Instruction in History Education – A Subject-specific Analysis of Why and How

open access: yesPanta rei
Differentiated instruction is an approach to teaching in which teachers respond proactively to the needs and preferences of students in their classroom.
Wouter Smets
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Raiders of the Lost Archives: Searching for the Hidden History of Religious Education in England [PDF]

open access: yes, 2014
publication-status: PublishedChapter from History, Remembrance and Religious Education edited by S. G. Parker, R. Freathy & L. J. Francis.This chapter provides a justification for historical inquiry in Religious Education research and a critique of the ...
Freathy, R.J.K.   +2 more
core  

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