Results 101 to 110 of about 952,979 (268)
TARİH BÖLÜMÜ ÖĞRENCİLERİNİN AİLE TARİHİ ÖĞRETİMİ ÖNEMİ ÜZERİNE GÖRÜŞLERİNİN İÇERİK ANALİZİ
Turkish History Education Journal, 2018 Tarih eğitiminde yerel tarih ve sözlü tarih önemli yer tutmaktadır. Sözlü tarih alanında temel konulardan birisi de aile tarihidir. Akademik alanda dünya ve Türk tarihine yön vermiş aileler üzerine araştırmalar yapılmıştır.
Özgür AKTAŞ +2 more
doaj
Nordic Journal of Educational HistoryThis article explores relationships between ideas of reform pedagogy and conceptions of history education in the writings of four Norwegian upper secondary school history teachers who worked at the same rural gymnasium, Eidsvoll landsgymnas (ELG ...
Anne Helene Høyland Mork
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
1950’LERİN POPÜLER TARİH DERGİSİ “RESİMLİ TARİH MECMUASI”NDA TARİH EĞİTİMİ ve ÖĞRETİMİ
Turkish History Education Journal, 2018 Bu çalışmanın amacı, 1950’lerin popüler tarih dergisi “Resimli Tarih Mecmuası”ndaki tarih eğitimi ve tarih öğretimini incelemektir. Araştırmada nitel araştırma yöntemlerinden belgesel (documentary) araştırma kullanılmıştır. Araştırmanın çalışma evrenini,
Mehmet ELBAN
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Conceptual history and History of Education
Historia de la Educación, 2013 After noting the importance of linguistic turn in the field of historiography, the two leading currents in the field of conceptual history are identi- fied, the Cambridge school and Reinhart Koselleck’s Begriffsgeschichte. The paper focuses on the analysis of the latter trend in conceptual history, linked to the phi- losophical (Heidegger, Gadamer ...
openaire +1 more source