Results 101 to 110 of about 4,536,174 (312)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fostering cognitive strategies for learning with 360° videos in history education contexts. [PDF]
Unterrichtswissenschaft, 2022 Nachtigall V +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Using Historical Sites in East Kalimantan for Education: Challenges and Opportunities
Yupa: Historical Studies Journal, 2018 The historical site can be used as a source of learning history, a model of learning history, media history learning, to enhance literacy history or as historical attractions.
Muhammad Azmi
doaj +1 more source
The Technological Education Institutes (TEI) in Greece and their libraries [PDF]
, 1999 The legal framework for the foundation of the Technological Education Institutes (TEI) in Greece is presented. A short history of the education of the librarians in Greece and some general information about all the Institutes and their libraries is ...
Elissaiou, Anastasia +2 more
core
Teachers' adoption of inquiry-based learning activities : the importance of beliefs about education, the self, and the context [PDF]
, 2018 Even though studies have shown that the impact of professional development on inquiry-based learning (IBL) tends to remain limited when it fails to consider teachers' beliefs, there is little known about how these beliefs influence teachers' adoption of ...
De Wever, Bram, Voet, Michiel
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Educar em Revista, 2011 This paper discusses the nature of argument and its role and importance in historical learning. The paper describes pedagogic strategies developed to help school pupils understand what argument is, model how arguments work and think about how arguments ...
Arthur Chapman
doaj +1 more source
Openness and education: a beginner’s guide [PDF]
, 2017 While recent high-profile developments such as Massive Open Online Courses (MOOCs) have placed renewed emphasis on the idea of openness in education, different notions of open in relation to education can be found dating back to the 1960s.
Jordan, Katy, Weller, Martin
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source