Results 91 to 100 of about 4,536,174 (312)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Effectiveness of Case-Based and Project-Based Learning in Promoting Sustainability Awareness: A Comparative Study

Journal of Education Technology
History learning, which is still dominated by conventional methods, tends to focus only on the cognitive aspect and has not fully addressed the affective and conative dimensions that are crucial in fostering students’ ecological awareness.
Khusnul Khotimah, Mochamad Kamil Budiarto, Arsyananda Rabbani, Leni Marpelina, Leo Andrew B. Biclar   +4 more
doaj   +1 more source

Fostering Secondary Students' Historical Thinking: A Design Study in Flemish History Education. [PDF]

J Form Des Learn, 2023
Wilke M, Depaepe F, Van Nieuwenhuyse K.
europepmc   +1 more source

A History of Business Education as Seen by a Bryant College Administrator [PDF]

, 1973
The history of Bryant and business education as seen by Nelson T.
Gulski, Nelson T.
core   +1 more source

The British Library and the impact of research [PDF]

, 1999
Gives a critical history of the British Library approach to research and how it failed fully to engage with the Higher Education sector as it launched on a golden period od library research stimulated by the Follett ...
Law, Derek
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A Hypermedia-Supported program and its effect on developing historical reasoning skills among first year secondary school students [PDF]

International Journal of Instructional Technology and Educational Studies
This study investigated the effect of a hypermedia-supported program on developing historical reasoning skills among first-year secondary school students in Egypt.
kholoud ibrahem, Samia Fayed
doaj   +1 more source

The effect of online learning in modern history education. [PDF]

Heliyon, 2022
Malysheva O, Tokareva E, Orchakova L, Smirnova Y.   +3 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Are College Students Interested in Family Health History Education? A Large Needs Assessment Survey Study. [PDF]

Int J Environ Res Public Health, 2023
Li M, Kwok OM, Ma P, Tseng TS, Chen LS.
europepmc   +1 more source