Results 91 to 100 of about 7,621,160 (294)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Towards a revision of the Palaearctic species of Aphodius Hellwig, 1798, subgenus Liothorax Motschulsky, 1860 (Coleoptera, Scarabaeidae, Aphodiinae) [PDF]

open access: yesZooKeys
The Palaearctic species of Aphodius Hellwig, 1798, subgenus Liothorax Motschulsky, 1860 are revised using a combination of chromosome analysis, molecular phylogenetics and morphological statistical analysis.
Robert B. Angus   +3 more
doaj   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

1. Introduction

open access: yes, 1958
Vastly increased research and a sounder technique in history in the nineteenth century had two influences on the social sciences. When an enthusiasm for the records of history was combined with the evolutionary perspective, it often resulted in the ...
Bloom, Robert L.   +6 more
core  

The production of ideas: Notes on Austrian intellectual history from Bolzano to Wittgenstein [PDF]

open access: yes, 1981
This paper takes the form of a series of sketches of 19th century Austrian political and intellectual history, allied with a number of more general reflections designed to contribute to our understanding of some of the peculiar characteristics of ...
Smith, Barry
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

A Monument to Culture and Achievement: The Samurai Suit of Armor and Katana at Gettysburg College [PDF]

open access: yes, 2018
Of the many artifacts found in Gettysburg College’s Musselman library, perhaps the most unusual and seemingly out of place may be the centuries-old replica of a samurai suit and katana standing guard over visitors and students from an oversized glass ...
Hauk, Carolyn
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Israelite Temples: Where Was Israelite Cult Not Practiced, and Why

open access: yesReligions, 2019
Most scholars in the late 20th and early 21st century believed that cultic activity in the kingdoms of Israel and Judah was practiced in various temples that were scattered throughout the kingdoms.
Avraham Faust
doaj   +1 more source

Featured Piece

open access: yes, 2018
This year the General Editors continued the tradition started last year by creating a feature piece to show our appreciation for the History Department.
Bamba, Abou B.   +3 more
core  

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