Results 111 to 120 of about 2,409,047 (263)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Distinguishing bipolar disorder from unipolar depression in general practice: A systematic review. [PDF]

Eur J Gen Pract
Niktabe DS, Massoubre C.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Development of national consensus-based recommendations for history taking, examination and clinical management of infants in chiropractic practice. [PDF]

Chiropr Man Therap
Overgaard FG, Hestbæk L, Davidson E.
europepmc   +1 more source

General History, History in the Detail

Critique d’art, 1997
openaire   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A Cardiovascular Care Pathway Supported by Remote Patient Management in Dutch Primary Care: Cost-Effectiveness, Budget Impact, and Workload Analysis. [PDF]

JMIR Mhealth Uhealth
Heijdra Suasnabar J, Rakers M, van Hattem N, Hiddink E, Haas M, Zhang X, Atsma D, Bonten TN, van den Akker-van Marle ME, van Os HJA.   +9 more
europepmc   +1 more source

LEGAL HISTORY AND GENERAL HISTORY

Bulletin of the Institute of Classical Studies, 1996
openaire   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Hypertensive Disorders of Pregnancy and Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Hypertension
Ezzat D, Pabon MA, Li L, Chang A, De Moor N, Yu Z, Cho SMJ, Natarajan P, Spracklen CN, LeBlanc ES, Eaton CB, LaMonte MJ, Stefanick ML, Manson JE, Parikh N, Reiner AP, Roh JD, Soria-Contreras DC, Hoshi RA, Mora S, Demler OV, Powe CE, Honigberg MC.   +22 more
europepmc   +1 more source