Results 121 to 130 of about 7,680,795 (352)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
General relativity’s energy and positivity: a brief history [PDF]
, 2021 S. Deser
openalex +1 more source
How useful is anthropometric history? [PDF]
In his recent presidential address to the American Economic History Association, Paul Hohenberg argued that anthropometric history does not meet his criteria for useful research in the field of economic history.
Komlos, John
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The production of ideas: Notes on Austrian intellectual history from Bolzano to Wittgenstein [PDF]
, 1981 This paper takes the form of a series of sketches of 19th century Austrian political and intellectual history, allied with a number of more general reflections designed to contribute to our understanding of some of the peculiar characteristics of ...
Smith, Barry
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2018 This year the General Editors continued the tradition started last year by creating a feature piece to show our appreciation for the History Department.
Bamba, Abou B. +3 more
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Amoroso Costa e o primeiro livro brasileiro sobre a Relatividade Geral
Revista Brasileira de Ensino de FísicaEm 1922, o físico-matemático brasileiro Amoroso Costa publicou um livro de introdução à Teoria da Relatividade. Este livro, um dos primeiros textos sobre o assunto no mundo, surpreende ainda hoje pela sua limpidez, precisão e concisão.
Jean Eisenstaedt, Júlio C. Fabris
doaj +1 more source