Results 81 to 90 of about 2,099,771 (306)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Literární komparatistika, areálová/kulturní studia, teorie literárních dějin a problém hodnoty v současné literárněvědné praxi

Opera slavica, 2013
The author of the present study deals with the crucial and topical problems concerning both the comparative studies and area/cultural studies as we ll as the history and theory of national literatures and the comparative studies and their methodology in ...
Ivo Pospíšil
doaj  

REVOLUTION FROM THE RIGHT: THE RUSSIAN BLACK HUNDREDS MOVEMENT AND ITS PLACE IN THE HISTORY OF EUROPEAN FAR RIGHT PARTIES AND MOVEMENTS Part II-I: the Black Hundred understanding of Russianness in the general European context of the history of nationalism and the consolidation of nations: origins and development of varieties of nationalism in the Russian Empire and Europe

Historical and social-educational ideas, 2018
This series of articles investigates the Black Hundreds’ understanding  of Russianness in the general European  context of the history of nationalism. In brief, Russianness is the  totality of nationally specific characteristics that define Russians as  Russians and that distinguish Russians from other peoples.
openaire   +1 more source

Willi Graf of the White Rose: Transformation of an Image (poster session) [PDF]

, 2011
My dissertation focuses on Willi Graf of the student resistance group called the White Rose. While the history of the White Rose is well known in Germany and possibly Europe in general, Willi Graf’s story and significant contribution to the group is ...
Richards-Wilson, Stephani
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Exiles from the Netherlands: A Rhizomatic Approach to Dutch Hip Hop History

Tijdschrift voor Mediageschiedenis
Mainstream canonisation of Hip Hop history in the Netherlands has mainly focused on the country’s West, and often relegates anglophone rap to a footnote in favour of Dutch-language rap. I offer an alternative reading by approaching the Netherlands’ early
Dastan Abdali
doaj   +1 more source

Europe: Institutional structure for security since the Peace of Westphalia / Europa: Estructura institucional para la seguridad desde la Paz de Westfalia

Barataria, 2008
The present work seeks to carry out a succinct revision of the most significant events in the long historical process that have determined the institutional structure for the security in Europe from the Peace of Westphalia.
Francisco José Blanco Jiménez, Alberto Romero Ania   +1 more
doaj   +1 more source

Psychological care of women with a family history of breast cancer [PDF]

, 2005
In parallel to the development of clinical cancer genetics services for women with a significant history of breast cancer, there has been a growing need to identify the psychological sequelae to risk ascertainment, predictive genetic testing and ...
Hopwood, Penelope
core   +1 more source

Pollen-based quantitative reconstructions of Holocene regional vegetation cover (plant-functional types and land-cover types) in Europe suitable for climate modelling [PDF]

, 2014
We present quantitative reconstructions of regional vegetation cover in north-western Europe, western Europe north of the Alps, and eastern Europe for five time windows in the Holocene [around 6k, 3k, 0.5k, 0.2k, and 0.05k calendar years before present ...
Barratt, P., Birks, H. J. B., Bjorkman, L., Bjune, A. E., Broström, Anna,, Caseldine, C., David, R., Dodson, J., Doerfler, W., Fischer, E., Fyfe, R., Gaillard, M. -J., Giesecke, T., Hultberg, T., Kalnina, L., Kangur, M., Koff, T., Kunes, P., Lageras, P., Latalowa, M., Lechterbeck, J., Leroyer, C., Leydet, M., Lindbladh, M., Lund University., Lund University., Lund University., Lund University., Marquer, Laurent,, Mazier, F., Mitchell, F. J. G., Nielsen, Anne Birgitte,, Odgaard, B. V., Peglar, S. M., Persson, Thomas,, Poska, Anneli,, Roesch, M., Seppa, H., Sugita, S., Trondman, A. -K., Twiddle, C., van der Knaap, P., van Geel, B., Veski, S., Wick, L.   +44 more
core   +7 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source