Hacia una historiografía de la enfermedad: Prácticas, profesiones y enfermos
Memoria y Civilización, 2008 The article considers the development of the history of medicine since its institutionalization, in 19th century Europe. The historiographical tendencies that conditioned this development of the branch of learning are analysed.
Pilar León Sanz
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
La “potenza del negativo” come destino dell’Europa: un libro di Biagio de Giovanni [PDF]
Democrazia e Diritti SocialiIn this contribution we analyze the constitutive connection of Europe and philosophy in the thought of Biagio de Giovanni, within a properly ‘ontology’ field, according to a ‘fundamental speculative figure’ which is articulated in an ‘ontology of being ...
Antonio Luongo
doaj
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Why Religion Matters: Montenegro’s Sacred Nationhood in a Time of Contestation
Colloquia HumanisticaThis book review offers a critical assessment of Emil Hilton Saggau’s Nationalisation of the Sacred. Although Saggau’s work seems to propose a concise history of Montenegro through the lens of Orthodox historiography, the main argumentation provides ...
Francesco Trupia
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
A survey of articles in the Newsletter of the EMS about the history and activities of full member Societies of the EMS (Issue 1, September 1991 – Issue 104, June 2017) [PDF]
, 2017 In order to have a clearer idea of what has been published and so to be able to plan future actions, the Editorial Board of the Newsletter has recently compiled a survey of articles on the history and activities of full member societies of the EMS.
Costa, Fernando Pestana da
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
The Material Culture of Road Safety: Road Safety as Museum Display?
Journal of Road Safety, 2009 The museum does not usually spring to mind as a site for road safety promotion but no other institution has so much involvement in collecting and displaying the material culture of motoring and interpreting its history for the general public.
Jennifer Clark
doaj
A genetic probe into the ancient and medieval history of Southern Europe and West Asia
Science, 2022 Iosif Lazaridis +204 more
semanticscholar +1 more source