Results 141 to 150 of about 13,191,531 (320)
History learning in the Merdeka Curriculum aims to develop critical thinking skills, national identity, and historical reflection through the active role of students (student-centered).
Miftakhul Munir +3 more
doaj +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
The aim of this article is to identify several reflexive issues related to scientific work in contemporary Turkey, within an authoritarian context marked by episodes of political violence.
Elif Can
doaj +1 more source
Generating Opportunity from Uncertainty [PDF]
Learning to deal with uncertainty makes organizations more robust. Leaders can take steps to help their organizations take advantage uncertainty. When continued success transitions from informed decision to luck, small differences in the ability of ...
King, David R.
core +1 more source
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Development Of Local History-Based Virtual Reality Media to Improve Practical History Skills
The acquisition of historical thinking skills is crucial for students, particularly in the areas of interpreting, documenting, and communicating information from diverse historical sources.
- Ofianto +3 more
doaj +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Learning and Communication in Sender-Reciever Games: An Economic Investigation [PDF]
This paper compares the performance of stimulus response (SR) and belief-based learning (BBL) using data from game theory experiments. The environment, extensive form games played in a population setting, is novel in the empirical literature on learning ...
Blume, A. +3 more
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source

