Results 41 to 50 of about 50,288 (215)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

USING GEOMATICS TO UNDERSTAND AND VALORIZE HERITAGE, THREE DIFFERENT CONTEXTS OF STUDY: SYRIA, ITALY, AND FRANCE [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Such innovative meeting dedicated to Cultural Heritage: challenges, new perspectives, and technological innovation are ‘vital’ in order to exchange different experiences, needs, opportunities, and, above all, to find new approaches to preserve, at least,
E. E. K. Hanna, A. Paonessa
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Research and development of helium-xenon Brayton cycle technology: A review

National Science Open
Helium-xenon Brayton cycle systems have significant potential as the energy conversion system for small-scale reactors in remote land, deep-sea, and space applications due to a range of advantages, including high cycle efficiency, compact system ...
Chen Weixiong, Song Meihui, Qian Yiran, Yu Hongxing, Yan Junjie   +4 more
doaj   +1 more source

Assisting you to advance with ethics in research: an introduction to ethical governance and application procedures

International Journal for Educational Integrity, 2021
Ethics and ethical behaviour are the fundamental pillars of a civilised society. The focus on ethical behaviour is indispensable in certain fields such as medicine, finance, or law. In fact, ethics gets precedence with anything that would include, affect,
Shivadas Sivasubramaniam, Dita Henek Dlabolová, Veronika Kralikova, Zeenath Reza Khan   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Aplicaciones docentes de las TIC para el desarrollo de recursos didácticos en Radiología: Una trayectoria de trabajos en equipo en la universidad

Red U, 2012
Se presenta en el artículo uno de los casos incorporados a una tesis doctoral en desarrollo sobre equipos docentes en el ámbito universitario. El profesor del que parte el análisis del caso pertenece al Departamento de Radiología y Medicina Física de la ...
Laura Lodeiro Enjo
doaj   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Basic research, lethal effects: Military artificial intelligence research funding as enlistment

Big Data & Society
In the context of unprecedented U.S. Department of Defense (DoD) budgets, this paper examines the recent history of DoD funding for academic research in algorithmically based warfighting. We draw from a corpus of DoD grant solicitations from 2007 to 2023,
David Gray Widder, Sireesh Gururaja, Lucy Suchman   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source