Results 91 to 100 of about 1,254,121 (350)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Historical sociology of the city [PDF]

open access: yes, 2003
About the book: This Handbook consists of 26 chapters on historical sociology. It is divided into three parts. Part One is devoted to Foundations and covers Marx, Weber, evolutionary and functionalist approaches, the Annales School, Elias, Nelson and ...
Isin, Engin F.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Image as a Communication Tool for Virtual Museums. Narration and the Enjoyment of Cultural Heritage

open access: yesProceedings, 2017
The challenge of contemporary museums is to make content accessible to a wider audience; in this way information related to the good becomes more communicative and usable in order to enhance its uniqueness.
Andrea Casale   +2 more
doaj   +1 more source

Looking Out, Looking In: Contemporary Artists from Morocco [PDF]

open access: yes, 2019
This is the catalogue of the exhibition "Looking Out, Looking In: Contemporary Artists from Morocco" held at Faye G., Jo, and James Stone Gallery 855 Commonwealth Avenue from February 8, 2019 – March 31, 2019. The exhibition is curated by Cynthia Becker,
Becker, Cynthia, Sabri, Nadia
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Voices from Two Historical Identities Dwelling as a Matter of Being [PDF]

open access: yes, 2014
The following paragraphs are based on my personal experience of study and life between Italy and Albania and are going to 'use' the history of architecture in two different contexts: the first one is the physical context of the city.
Guza, Kamela
core  

ANTARES: Progress towards building a `Broker' of time-domain alerts

open access: yes, 2016
The Arizona-NOAO Temporal Analysis and Response to Events System (ANTARES) is a joint effort of NOAO and the Department of Computer Science at the University of Arizona to build prototype software to process alerts from time-domain surveys, especially ...
Axelrod, Tim   +15 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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