Results 91 to 100 of about 167,744,003 (294)

History and theory of Islamic architecture

open access: yes, 2019
Islamic architecture is a misunderstood subject. Quite often, as elementary -- and even trivial -- themes as defining Islamic architecture, the relationship between Muslim and Islamic architecture, and the prospect of existence of un-Islamic ...
Spahic, Omer
core  

Thinking Design: Towards an Architecture of Critical Indeterminacy and Temporal Affectivity [PDF]

open access: yes, 2018
The legacy of Platonic thought and education in the West has led to a narrowing of what we call “thinking.” In particular, this legacy has led to modes of thinking that overvalue linear logic, objective facts, and universal constants, overlooking those ...
Teal, Randall
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Building Advocacy ‐ Who Builds Your Architecture?

open access: yes, 2016
Presented on March 2, 2016 at 2:00 p.m-4:00 p.m. in the Reinsch-Pierce Family Auditorium, College of Architecture at Georgia Tech.Mabel 0. Wilson received a doctorate in American Studies from NYU in 2007 and an M.
Wilson, Mabel O.
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The feminist practice nowadays. New ways of doing History of Architecture

open access: yes
Starting from her research and practise, Bianca Felicori spoke with Silvia Franceschini, senior curator at CIVA Brussels, about feminist practice nowadays.
Felicori, Bianca   +1 more
core  

THE WARBURG INSTITUTE AND ARCHITECTURAL HISTORY

open access: yesCommon Knowledge, 2012
At first sight, classical architecture, with its continuous revivals and reworking of the forms of Greek and Roman building, would appear to offer a privileged field in which to apply Warburg's central notion of the survival of classical forms (Nachleben der Antike) and his view of art history's unfolding as a process of remembrance (or Mnemosyne). Yet
openaire   +2 more sources

Home - About - Disclaimer - Privacy