Results 81 to 90 of about 1,254,121 (350)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Introduction To German Studies: The Romantics Then And Now (GMST 20) Syllabus [PDF]

, 2018
This course serves as an introduction to the interdisciplinary field of German Studies. German culture has played a seminal role in the history and culture of modern Europe, influencing and shaping the European spirit in all manner of ways.
Meirosu, Madalina
core   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Layers in the Fabric of Mind: A Critical Review of Cognitive Ontogeny [PDF]

, 2006
The essay is critically examines the conceptual problems with the influential modularity model of mind. We shall see that one of the essential characters of modules, namely informational encapsulation, is not only inessential, it ties a knot at a crucial
Nagarjuna, G.
core  

Interaction Histories and Short-Term Memory: Enactive Development of Turn-Taking Behaviours in a Childlike Humanoid Robot [PDF]

, 2019
In this article, an enactive architecture is described that allows a humanoid robot to learn to compose simple actions into turn-taking behaviours while playing interaction games with a human partner.
Bruner, Cangelosi, Corkum, Cowan, Crutchfield, Dautenhahn, Hutto, Johnson, Juscyck, Kaye, Mirza, Nadel, Nehaniv, Noë, Quick, Robins, Tani, Trevarthen, Varela, Vygotsky, Wittgenstein   +20 more
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

NASTRAN as a resource in code development [PDF]

, 1975
A case history is presented in which the NASTRAN system provided both guidelines and working software for use in the development of a discrete element program, PATCHES-111.
Crain, L. M., Neu, T. F., Stanton, E. L.
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Craft and Repair Heritage: From Capture to Dissemination in Digital Space [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The preservation of construction and repair knowledge necessitates a shift from static documentation toward the dynamic capture of the embodied and collaborative nature of craft.
L. Crouzet, A. L. Pöllinger, S. Langenberg   +2 more
doaj   +1 more source

Fischer auf der Reise nach Stonehenge [PDF]

, 2013
On 26 July 1721, the Wiener Diarium informs its readers that a new book by the general surveyor of constructions, Johann Bernhard Fischer von Erlach, is ready and that the ones who had pre-ordered their copy could go and pick it up at the architect’s ...
Tamburelli, Pier Paolo
core