Results 81 to 90 of about 167,744,003 (294)
Proceedings, 2017 The challenge of contemporary museums is to make content accessible to a wider audience; in this way information related to the good becomes more communicative and usable in order to enhance its uniqueness.
Andrea Casale +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
An Architecture Story: Engaging Design Through Storytelling [PDF]
, 2015 There are many historic pieces of architecture that are centuries old, but still somehow maintain the same level of magnificence and delight as they had when they were first completed.
Shek, Chuen Ho Howard
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A repurposed space: City God Temple as National Products Exhibition Hall in Guangzhou, 1928 to 1937
Journal of Asian Architecture and Building EngineeringGuangzhou’s City God Temple, originally built in 1370, remained one of Guangzhou’s most-enduring examples of architectural heritage well into the twentieth century, especially between 1928 and 1937.
Liu Xiaoqing
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
School of Architecture + Design reception, CAUS 50th anniversary
, 2014 The original version of Fields + Array was exhibited at the Moss Arts Center then temporarily installed on Burchard Plaza. For the Architecture + Design reception, the concrete cylinders were recast, metal rods were inserted, and paper lanterns with self-
Ridgeway, Matthew +5 more
core
Architectural HistoriesThis article explores the post-war historiography of Dutch modern architecture by focusing on the Dutch reception of Giovanni Fanelli’s Architettura moderna in Olanda 1900–1940 [Modern architecture in the Netherlands 1900–1940]. Written in 1968, the book
rixt hoekstra
doaj +2 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source