Results 51 to 60 of about 188,790 (259)

Public Leisure Architecture in Colombia, or the Governance of Free Time, 1934–2021

Dearq
From "exclusive luxury" to "labor right," and from a space for amusement to one for disconnection, public leisure architecture in Colombia reflects a shift toward democratizing a practice once reserved for elites—now recognized as an indicator of quality
William García Ramírez
doaj   +1 more source

Parametric Grammar: The Shape of Villa Giulia, between Cognitive Coherence and Data Enrichment

Disegnare con, 2021
The research theme is the identification of a prototype procedure for the construction of parametric models useful for the communication of Cultural Heritage.
Francesca Guadagnoli, Elena Ippoliti, Andrea Casale   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Semantic Classification Approach for the Aachen Cathedral [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper presents a semantic classification workflow applied to the UNESCO World Heritage site of Aachen Cathedral, integrating 3D survey data and Machine Learning (ML) techniques.
M. Attenni, R. Barni, C. Bianchini, M. Griffo   +3 more
doaj   +1 more source

Ugliness in architecture in the Australian, American, British and Italian milieus: Subtopia between the 1950s and the 1970s

City, Territory and Architecture, 2022
The article examines the reorientations of the appreciation of ugliness within different national contexts in a comparative and relational frame, juxtaposing the Australian, American, British and Italian milieus.
Marianna Charitonidou
doaj   +1 more source

Architectural History As a Dynamic Process

Peristil : zbornik radova za povijest umjetnosti, 2023
Renate Wagner-Rieger focused her research on Austrian medieval architecture in addition to her studies of the ”Wiener Ringstrasse” especially when she participated in significant public Middle Ages art exhibitions. The shows were supported by catalogue essays, which were finally collected in her final book.
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Retour aux ordres. David Watkin (1941-2018) : l’écriture de l’histoire de l’architecture et le réveil conservateur

Perspective
This article explores the methodological approach of architecture historian David Watkin and his underlying political intent. From 1970 on, Watkin was a fellow at Peterhouse, the oldest of Cambridge University’s colleges, where a circle of conservative ...
William Terrier
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source