Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson +6 more
wiley +1 more source
Prevalence, Disease Onset and Clinical Outcome in Arginase 1 Deficiency: Cross-Border Surveillance in Germany, Austria, and Switzerland. [PDF]
Scharre S +19 more
europepmc +1 more source
Abstract Maternal and neonatal morbidity and mortality have declined dramatically during the last century. Historical data are therefore important sources to study the evolutionary selection pressures related to childbirth and how they have fluctuated over time.
Mirella Woodert +7 more
wiley +1 more source
SOD1 Variants in Patients With Amyotrophic Lateral Sclerosis in Central Eastern Europe: From Genetic Testing to SOD1 Targeted Therapy. [PDF]
Khazaal M +20 more
europepmc +1 more source
Human evolution and the obstetrical dilemma: The pelvic floor hypothesis
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley +1 more source
The “costly son” hypothesis: Sons exacerbate obstetrical dilemmas in humans and other mammals
Abstract Human childbirth has often been considered uniquely difficult among mammals, yet recent evidence suggests that obstructed labor and fetopelvic disproportion are widespread across placental mammals. Here, we propose the “costly son” hypothesis: because male offspring are typically larger at birth, they impose greater obstetric risk on mothers ...
Nicole D. S. Grunstra +1 more
wiley +1 more source
Semaglutide in peripheral artery disease and diabetes by baseline disease severity and age: the STRIDE trial. [PDF]
Nordanstig J +9 more
europepmc +1 more source
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma +9 more
wiley +1 more source
Electroanatomic Voltage-Guided Endomyocardial Biopsy for the Diagnosis of Isolated Cardiac Sarcoidosis. [PDF]
Wörgötter KM +8 more
europepmc +1 more source
Purpose To assess clinical, functional, and radiographic outcomes as well as return‐to‐sports (RTS) rates in adolescent patients (aged 10‐19 years according to the World Health Organization) who underwent the Latarjet procedure. Methods A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta ...
Peter Rab +7 more
wiley +1 more source

