Results 131 to 140 of about 168,529,466 (299)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Notes on Central Europe from Sociological Perspective

open access: yes, 2007
The following article is an attempt to establish whether the Central Europe of the 20th century is indeed a specific, internally homogenous socio-cultural macro-region. Two mutually complementary approaches were used. One is an analysis of the measure of
Jiří Musil
core   +1 more source

Supporting Successful Migration in Europe and Central Asia

open access: yes
The Journey Ahead: Supporting Successful Migration in Europe and Central Asia provides an in-depth analysis of international migration in Europe and Central Asia (ECA) and the implications for policy making.
Garrote Sánchez, Daniel   +2 more
core   +1 more source

Catholicism and anti-communism: the reactions of Irish intellectuals to revolutionary changes in Hungary (1918-1939)

open access: yesDiacronie. Studi di Storia Contemporanea, 2018
Although far from the centres of conflict on the Continent, interwar Ireland was also exposed to the influence of extreme left and right-wing political movements. Overall, most Irish nationalists adopted an uncompromisingly anti-Communist stance and used
Lili Zách has received her Masters Degrees in English (with specialization in Irish Studies) and History at the University of Szeged, Hungary, in 2006. She completed a PhD at the National University of Ireland, Galway, focusing on Irish perceptions of the small successor states of Austria-Hungary, 1914-1945. Her primary research interest lies in the field of Irish and Central European history in a transnational framework, with special attention to Irish links with Continental Europe in the first half of the twentieth century.
doaj  

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

open access: yesAging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara   +3 more
wiley   +1 more source

Too Small to Succeed? East Central Europe and the Historical Study of State Assessment

open access: yesZeitschrift für Ostmitteleuropa-Forschung, 2020
Klaus Richter, Heidi Hein-Kircher
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

State of democracy, human rights and the rule of law: a security imperative for Europe

open access: yes, 2016
An analysis of democracy, human rights and the rule of law in Europe, based on the findings of the Council of Europe monitoring mechanisms and bodies. This is the third annual report of the Secretary General on the state of democracy, human rights and ...
Council of Europe
core  

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