Results 121 to 130 of about 3,421,831 (294)
Poland in Times of Great War and Second Independence 1914–1939 [PDF]
, 2015 The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Pietrzak, Jacek
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Poland’s Integration with the European Union [PDF]
, 2015 The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Błaszczyk, Maria Celina
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Looking Out, Looking In: Contemporary Artists from Morocco [PDF]
, 2019 This is the catalogue of the exhibition "Looking Out, Looking In: Contemporary Artists from Morocco" held at Faye G., Jo, and James Stone Gallery 855 Commonwealth Avenue from February 8, 2019 – March 31, 2019. The exhibition is curated by Cynthia Becker,
Becker, Cynthia, Sabri, Nadia
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Digging in or building bridges? A scoping review of thematic analysis
Frontiers in Research Metrics and AnalyticsThis scoping review deals with a major trend in qualitative data analysis: thematic analysis (TA) that provides a general framework to develop relatively transparent processes; TA thus helps mitigate long-standing concerns with allegedly subjective ...
Christian Herzog +2 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Parasites provide evidence for fish consumption among Iron Age Siberian pastoralists
Scientific ReportsThe subsistence economies of prehistoric pastoralists of the Eurasian steppes have long been viewed through an oversimplified model of reliance on domesticated animals.
Sergey Slepchenko +4 more
doaj +1 more source
Археология евразийских степейThe archaeology of the Kola Peninsula is related to the archaeology of neighboring regions. The Early Neolithic (~5.3–4 millennia BC) is characterized by the Säräisniemi 1 ceramics of the two Varzina and Chavanga variants and the Pit-Comb, bifacial stone
Evgeniy M. Kolpakov +3 more
doaj +1 more source