Results 171 to 180 of about 6,995,982 (396)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Oral History as Inquiry: Using Digital Oral History Collections to Teach School Desegregation [PDF]

open access: yes, 2018
A body of literature in both history and history education indicates that when it comes to contemporary historical issues, oral history is one of the essential sources to investigate the past, particularly as a source for “history from below ...
Daugherity, Brian J., Suh, Yonghee
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Controlling the Brantas river: construction and impact of Japan-supported irrigation infrastructure on the agricultural economy and the environment in East Java

open access: yesCogent Arts & Humanities
This article examines the crucial role played by Japan in the development of irrigation infrastructure in Indonesia from the 1960s to the 1990s. While the assistance provided by Japan in irrigation infrastructure significantly enhanced the prominence of ...
Nawiyanto   +3 more
doaj   +1 more source

The development of technology education internationally [PDF]

open access: yes, 2009
The development of technology education within countries and regions is set within the historical, cultural, and political environment. Curriculum, teacher education, and in fact educational research do not sit in isolation from these.
Jones, Alister
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

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