Results 191 to 200 of about 4,530,314 (306)

Bridging Theory and Practice: a qualitative study on electronic charting and health systems science in Korean medicine education in alignment with KAS2022. [PDF]

J Pharmacopuncture
Lee WT, Kim BM, Choi HY, Kim SK, Park SE.   +4 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Online education and its relation to hearing status among higher-secondary students in Bangladesh: A cross-sectional survey. [PDF]

PLoS One
Tabassum Hridi ST, Iktidar MA, Kabir KS, Ghosh P, Tamjid A, Al Zaber A, Babu RT, Mehzabeen M, Das Gupta A, Chowdhury S, Roy S.   +10 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

History of Science in Education [PDF]

Nature, 1948
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Interacting and joint effects of atherogenic index of plasma and dietary inflammatory index on hypertension-diabetes comorbidity risk in Chinese elderly adults: results from China Nutrition and Health Surveillance in 2015-2017. [PDF]

Front Nutr
Wu X, Fang H, Lu B, Wang H, Du W, Li S, Guo Q, Wei X, Gong W, Hua L, Ju L.   +10 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Developing and Validating a Coding Scheme for Clinical Reasoning in History Taking Using Generative AI-Based Virtual Patients: Systematic Text Condensation Approach.

JMIR Med Educ
Chen N, Tang L, Liu Y, Lin C, Li Z, Shi C, Xia M, Gasevic D, Gasevic D, Zheng J, Fan Y, Li X.   +11 more
europepmc   +1 more source