Results 91 to 100 of about 245,985 (307)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

An Outlook of the Fashion Industry Through Fashion History

open access: yesProcedia - Social and Behavioral Sciences, 2012
AbstractIn this presentation, survival theories and visuals of the Kaunake garments which have historic roots in Sumerian Civilization around 2500 BC to present in the eye of fashionable textile have been presented.For most people; FASHION is the most important word and part of our life, the way of our living in a fast changing world.
openaire   +1 more source

Ralph Rucci at the Queer History of Fashion Symposium

open access: yes
Fashion designer Ralph Rucci presents “The Greatest Gay Fashion Designers” at The Museum at FIT’s 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full talk, which is available for check out at

core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Drum magazine project: A decolonial shift in teaching fashion theory and history

open access: yesDiscern
The Drum Magazine Project is a cross-institutional teaching and research project designed to explore a decolonial approach to teaching fashion theory and history.
Khaya Mchunu, Kiara Gounder
doaj   +2 more sources

Professor Christopher Breward at the Queer History of Fashion Symposium

open access: yes
Professor Christopher Breward, professor of cultural history at the University of Edinburgh, presents the paper "Couture as Queer Auto/Biography" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.

core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Elizabeth Wilson at the Queer History of Fashion Symposium

open access: yes
Elizabeth Wilson, author and university lecturer in cultural studies, presents the paper "What Does a Lesbian Look Like?" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the

core  

The social lives of UK fashion blogs

open access: yes, 2013
This thesis is the result of twenty-five months of ethnographic fieldwork, both online and offline, in the United Kingdom working with London-based fashion bloggers.
Eldred, Susan A
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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