Results 71 to 80 of about 245,985 (307)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Éditorial

open access: yesPerspective, 2023
Marine Kisiel, Matthieu Léglise
doaj   +1 more source

Written clothing : how fashion works in the street style photography blog

open access: yes, 2014
In this paper, I consider the street style blog through a close analysis of one of its most distinctive features—the combination of image and text—against Roland Barthes’ two distinct representations of the garment—image clothing and written clothing ...
De Perthuis, Karen (R17895)
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

100 Years of Fashion: Part Two

open access: yes
The Museum at FIT is excited to present 100 Years of Fashion, a two-part introduction to the history of fashion from the late 19th century through the 1990s. These two videos were originally created for high school students enrolled in FIT's Summer Live,

core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Les médias audiovisuels, l’autre vitrine de la création et des créateurs de mode

open access: yesIn Situ
The history and the economy of fashion are both closely linked to those of the media that it is difficult not to take those into consideration when drawing up an inventory of fashion heritage. The collections of the French national audiovisual institute (
Tiziana de Santis, Géraldine Poels
doaj   +1 more source

100 Years of Fashion: Part One

open access: yes
The Museum at FIT is excited to present 100 Years of Fashion, a two-part introduction to the history of fashion from the late 19th century through the 1990s. These two videos were originally created for high school students enrolled in FIT's Summer Live,

core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Les collections de vêtements d’enfant, problèmes et perspectives

open access: yesIn Situ
Children's fashion remains a marginal museological subject in the contemporary museographic landscape and in particular in the institutions that should be in charge of this topic: fashion and local history museums.
Aude Le Guennec, Clare Rose
doaj   +1 more source

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