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The Early History of Preventive Conservation in Great Britain and the United States (1850–1950)

CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2014
The early history of preventive conservation is characterized by the progressive integration of science into the museum world and the strengthening of collaboration between curators, conservators and scientists.
Simon Lambert
doaj   +1 more source

State-of-the-art in studies of glacial isostatic adjustment for the British Isles: a literature review [PDF]

, 2016
Understanding the effects of glacial isostatic adjustment (GIA) of the British Isles is essential for the assessment of past and future sea-level trends.
Alistair Rennie, Arıkan, Bekaert, Bingley, Bähr, Davenport, Elizabeth J Petrie, Firth, Firth, Firth, Jardine, Jim Hansom, Julia Stockamp, Kaneko, Lambeck, Li, Li, Paul Bishop, Peltier, Plag, Ringrose, Samsonov, Shennan, Shennan, Shennan, Shennan, Sissons, Sissons, Sissons, Smith, Smith, Smith, Tong, Van de Plassche, Wang, Woodroffe, Zhenhong Li   +36 more
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Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

“Federarsi o perire”. Il contributo britannico al federalismo europeo [PDF]

Diacronie. Studi di Storia Contemporanea, 2016
Great Britain had been entrenched behind the myth of a golden isolation which seemed destined to outlive the deep changes in the geopolitical balance of Europe between 19th century and 20th century.
Benedetta Giuliani
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جــــــون ميـــــجر نشأته وبداية حياته السياسية 1943- 1979 John Major His upbringing and the beginning of his political career1943-1979

Journal Of Babylon Center For Humanities Studies, 2021
The history of Britain received great attention from Western researchers in Europe and America, so they wrote hundreds of thousands of books on this important region of the world, and these studies extended from the beginning of the establishment of the ...
حسن أحمد ابراهيم المعموري Hassan Ahmed Ibrahim Al-Mamouri, قاسم كريم علي الجنابي Qasim Karim Ali Al-Janabi   +1 more
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Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ce que Charles Darwin doit à Joseph Banks

Comptes Rendus Biologies
History has remembered Joseph Banks as the explorer-botanist of the first voyage of James Cook. Yet, shortly after his return, he got elected president of the Royal Society and, for over 40 years, he then played in Great Britain an eminent role in ...
Le Guyader, Hervé
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Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Could the British Have Won the American War of Independence? [PDF]

, 2006
Streaming video requires RealPlayer to view.The University Archives has determined that this item is of continuing value to OSU's history.Jeremy Black is a Professor of History at the University of Exeter in Great Britain.
Black, Jeremy
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