Results 31 to 40 of about 733,507 (305)

Regional modelling of permafrost thicknesses over the past 130 ka: implications for permafrost development in Great Britain [PDF]

, 2015
The greatest thicknesses of permafrost in Great Britain most likely occurred during the last glacial–interglacial cycle, as this is when some of the coldest conditions occurred during the last 1 000 000 years.
Busby, Jonathan P., Kender, Sev, Lee, Jonathan R., Norris, Simon, Williamson, Paul   +4 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

State-of-the-art in studies of glacial isostatic adjustment for the British Isles: a literature review [PDF]

, 2016
Understanding the effects of glacial isostatic adjustment (GIA) of the British Isles is essential for the assessment of past and future sea-level trends.
Alistair Rennie, Arıkan, Bekaert, Bingley, Bähr, Davenport, Elizabeth J Petrie, Firth, Firth, Firth, Jardine, Jim Hansom, Julia Stockamp, Kaneko, Lambeck, Li, Li, Paul Bishop, Peltier, Plag, Ringrose, Samsonov, Shennan, Shennan, Shennan, Shennan, Sissons, Sissons, Sissons, Smith, Smith, Smith, Tong, Van de Plassche, Wang, Woodroffe, Zhenhong Li   +36 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Book review: the Scottish diaspora: understanding the forces which stimulate emigration [PDF]

, 2012
There are many detailed accounts of nineteenth-century emigrants, of their journeys and settlements abroad – but what of those they left behind? This book delves into the heart of Georgian Britain to explore the role that the men and women of the ...
Cameron, Ewen
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

“Federarsi o perire”. Il contributo britannico al federalismo europeo [PDF]

Diacronie. Studi di Storia Contemporanea, 2016
Great Britain had been entrenched behind the myth of a golden isolation which seemed destined to outlive the deep changes in the geopolitical balance of Europe between 19th century and 20th century.
Benedetta Giuliani
doaj  

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Ce que Charles Darwin doit à Joseph Banks

Comptes Rendus Biologies
History has remembered Joseph Banks as the explorer-botanist of the first voyage of James Cook. Yet, shortly after his return, he got elected president of the Royal Society and, for over 40 years, he then played in Great Britain an eminent role in ...
Le Guyader, Hervé
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source