Results 11 to 20 of about 69,195 (262)
THE STUDY OF HISTORY OF MATHEMATICS [PDF]
n ...
openaire +2 more sources
History of Mathematics in Mathematics Education : an Overview [PDF]
mathematica didactica, Vol. 42 No.
Clark, Kathleen M. +3 more
openaire +1 more source
Quem somos nós, professores de matemática?
Ao saber quem são seus avôs, bisavôs e mesmo tataravôs profissionais, o professor de matemática passa a ver o trabalho de seus colegas contemporâneos, e seu próprio fazer docente, de outro modo. Dá a seu ofício uma dimensão histórica.
Wagner Rodrigues Valente
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
La vita e l'opera di Józef Maria Hoene-Wrónski
This article is about Józef Maria Hoene-Wrónski (1776 - 1853), one of the most original figures in the history of science. The life and mathematical work of Hoene-Wrónski is presented in the historical and scientific context of Europe at his time.
Piotr Pragacz
doaj +1 more source

