Results 151 to 160 of about 3,662,534 (344)

Recycling the evidence: different approaches to the reanalysis of gerontological data [PDF]

open access: yes, 2005
In 1991 Professor Margot JEFFERYS and two colleagues interviewed "pioneers of geriatric medicine" of whom 60 were geriatricians. These data are now on disk and can be searched digitally. The interviews were long and focussed on the careers of the doctors
Bornat, Joanna
core   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Short-Course Chemotherapy for Tuberculosis [PDF]

open access: yes, 2005
Annotated and edite transcript of a Witness Seminar held on 3 February 2004. Introduction by Dr Linda Bryder, University of Auckland.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2005. ©The Trustee of the Wellcome Trust,
Christie, DA, Tansey, EM
core  

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Case History. College of Medicine Yearbook [PDF]

open access: yes, 1952
1952https://scholarworks.uvm.edu/dmlyearbook/1001/thumbnail ...
University of Vermont
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

THE STAGES OF THE HISTOLOGY FORMATION: THE ROLE OF SCIENTISTS AND THEIR CONTRIBUTION TO THE DISCIPLINE DEVELOPMENT

open access: yesБайкальский медицинский журнал
Relevance. Histology, which studies the microscopic structure of tissues, is the basis for many biomedical sciences. The study of the histology history helps to understand better how modern research and diagnostic methods were formed.
Lyubov A. Ivanova   +2 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

SARS-CoV-2: lessons from both the history of medicine and from the biological behavior of other well-known viruses. [PDF]

open access: yesFuture Microbiol, 2021
Fiorino S   +14 more
europepmc   +1 more source

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