Results 61 to 70 of about 6,221,845 (366)
FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
Interview with Huda Zoghbi [PDF]
, 2016 An oral history interview with Dr. Huda Zoghbi about her career at Baylor College of Medicine in the Texas Medical Center. She worked as a professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology and Neuroscience at Baylor ...
Zoghbi, Huda, MD
core +1 more source
Assisted Knowledge Graph Authoring: Human-Supervised Knowledge Graph Construction from Natural Language [PDF]
Encyclopedic knowledge graphs, such as Wikidata, host an extensive repository of millions of knowledge statements. However, domain-specific knowledge from fields such as history, physics, or medicine is significantly underrepresented in those graphs. Although few domain-specific knowledge graphs exist (e.g., Pubmed for medicine), developing specialized
arxiv +1 more source
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
, 2001 This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 6 June 2000. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2001.©The Trustee of the Wellcome ...
Christie, DA, Tansey, EM
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Cardiocentrism in ancient medicines
International Journal of Cardiology: Heart & Vasculature, 2023 History of cardiology starts scientifically in 1628, when William Harvey (1578–1657) published his revolutionary book Extercitatio anatomica de motu cordis et sanguinis in animalibus, where he described “general” circulation, movements and functions of ...
Fabio Zampieri +2 more
doaj
Giovanni de la Fontana, engineer and magician [PDF]
arXiv, 2013 Giovanni de la Fontana was a man of the Italian Renaissance of the early fifteenth-century. Besides becoming a doctor of medicine, he was an engineer who used his skills to mimic the magicians, creating a sort of "artificial magic".
arxiv
Histopathology of Third Trimester Placenta from SARS-CoV-2-Positive Women [PDF]
arXiv, 2020 Background: This study aims to investigate whether maternal SARS-CoV-2 status affect placental pathology. Methods: A retrospective case-control study was conducted by reviewing charts and slides of placentas between April 1 to July 24, 2020. Clinical history of COVID-19 were searched in Pathology Database (CoPath). Controls were matched with SARS-CoV-2-
arxiv
FEBS Letters, EarlyView.We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon +5 more
wiley +1 more source
, 1985 David Stove reviews Selwyn Grave's History of Philosophy in Australia, and praises philosophers for thinking harder about the bases of science, mathematics and medicine than the practitioners in the field. The review is reprinted as an appendix
Stove, D. C.
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