Results 101 to 110 of about 32,436 (310)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Urbanizace, industrializace, feminismus a ženské řeholní kongregace moderní doby: Několik poznámek k možnostem sociálních dějin k dalšímu výzkumu

open access: yesHistorická sociologie
The study deals with the typically modern phenomenon of European social and church history, which represents the origin and development of women’s religious congregations.
Tomáš Petráček
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

La muerte ante la batalla: Actitudes religiosas y mentalidades colectivas en Almansa a principios del siglo XVIII

open access: yesCuadernos de Historia de España
Durante la Edad Moderna, "guerra" y "muerte" fueron dos términos que estuvieron muy presentes en la sociedad europea. El comienzo del siglo XVIII en España vino marcado por la Guerra de Sucesión, trasformada por sus participantes en un conflicto ...
Ramón Cózar Gutiérrez   +1 more
doaj  

Process Philosophy and the Emergent Theory of Mind: Whitehead, Lloyd Morgan and Schelling [PDF]

open access: yes, 2002
Attempts to ‘naturalize’ phenomenology challenge both traditional phenomenology and traditional approaches to cognitive science. They challenge Edmund Husserl’s rejection of naturalism and his attempt to establish phenomenology as a foundational ...
Gare, Arran
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Review Essay: The Great Inspirator—Insights From the Workshop of the Historian Marc Bloch

open access: yesForum: Qualitative Social Research, 2002
Peter SCHÖTTLER's edition Marc Bloch. Aus der Werkstatt des Historikers. Zur Theorie und Praxis der Geschichtswissenschaft deals with 31 key-texts of the French historian of the Middle Ages and founding father of the Annales-School Marc BLOCH.
Volker Barth
doaj  

The Reception of Vernant in the English-Speaking World

open access: yesHistory of Classical Scholarship, 2020
Six Anglophone colleagues of Jean-Pierre Vernant (1914–2007) in Britain and the USA recall his influence on their lives and research: his importance for the history of mentalities and for the theory of alterity and structuralism are discussed, together ...
Oswyn Murray
doaj  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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