Results 81 to 90 of about 879 (266)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Review Essay: The Great Inspirator—Insights From the Workshop of the Historian Marc Bloch
Forum: Qualitative Social Research, 2002 Peter SCHÖTTLER's edition Marc Bloch. Aus der Werkstatt des Historikers. Zur Theorie und Praxis der Geschichtswissenschaft deals with 31 key-texts of the French historian of the Middle Ages and founding father of the Annales-School Marc BLOCH.
Volker Barth
doaj
The Reception of Vernant in the English-Speaking World
History of Classical Scholarship, 2020 Six Anglophone colleagues of Jean-Pierre Vernant (1914–2007) in Britain and the USA recall his influence on their lives and research: his importance for the history of mentalities and for the theory of alterity and structuralism are discussed, together ...
Oswyn Murray
doaj
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Images, mentalités, quantités : pour une histoire de l’art statistique
Perspective, 2013 Bernd Roeck
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Estudios de Historia Moderna y Contemporánea de México, 2009 En el presente artículo se ofrece una síntesis sobre el desarrollo de las corrientes historiográficas a lo largo de la segunda mitad del siglo XX. Asimismo se hace énfasis en el quiebre del paradigma de la historia de las mentalidades y el surgimiento ...
Martín F. Ríos Saloma
doaj
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source