Results 71 to 80 of about 2,342 (310)

‘Bringing it all back home’: mentalities, models and the historical study of religions

open access: yes, 2014
If historians of mentalities are studying cultural models of the past, the cognitive historians of religions are in their turn studying religious model.
Sjöblom, Tom
core  

Más allá de la historia oficial. Escritura doméstica y claves secretas en las cartas de los conquistadores del Nuevo Mundo

open access: yesCaravelle, 2013
The epistolary genre represents a source of historical information of extraordinary importance to reconstruct the complex world of mentalities as well as everyday life and social history in general.
Carmen Mena García
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Lieux de vie, lieux d’images : une autre histoire occidentale de l’espace domestique

open access: yesPerspective, 2021
Gil Bartholeyns   +5 more
doaj   +1 more source

L’histoire des sensibilités: un territoire-limite ? [The History of Sensibilities: A Borderline Territory?]

open access: yesCritical Hermeneutics, 2019
The history of sensibilities, emotions, the body are now in full renewal. Certainly, Lucien Febvre was already calling for this enrichment of the historian’s territory and the success of the history of mentalities in the seventies had already begun to ...
Quentin Deluermoz, Hervé Mazurel
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Kaupo as an Example of the Image of the Stanger in the History of Mentalities

open access: yes, 2015
Bakalaura darbā „Kaupo kā svešā un savējā tēla piemērs mentalitētes vēsturē” tiek aplūkota Latvijas teritorijas iedzīvotāju un atnācēju no Rietumeiropas mentalitāšu mijiedarbība 13. gadsimtā.
Buša, Inga
core  

Of old conflicts and new mentalities: Maravall\u27s place in the history of Spanish literature

open access: yes
Aparecido en el año 2024, el nuevo libro, Nuevos combates por la historia: Maravall y la literatura española,  del profesor de literatura, Miguel Ángel García (Universidad de Granada), plantea una sociología de la literatura discernida a partir de la ...
Fernández Lam-Sen, Elizabet
core   +1 more source

The fractured history of the mental hospital in Delhi

open access: yesIndian Journal of Psychiatry, 2018
The history of the mental hospital in Delhi is a fascinating story. Set up in colonial times, the asylum in Delhi seems to reflect the tumultuous and chaotic history of the city itself. It was perhaps established in the early 19th century, and functions till 1857, when it is ransacked in the Mutiny.
Jain, Sanjeev, Sarin, Alok
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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