Results 41 to 50 of about 169,245,677 (221)

Rapid range expansion predicted for the Common Grackle (Quiscalus quiscula) in the near future under climate change scenarios

open access: yesAvian Research, 2021
Background Climate change due to anthropogenic global warming is the most important factor that will affect future range distribution of species and will shape future biogeographic patterns.
Peter Capainolo   +2 more
doaj   +1 more source

Internet et le Grand Siècle : les recueils collectifs de poésie au regard du Web

open access: yesSillages Critiques, 2022
This article highlights existing but overlooked analogies between digital-age publications – on websites, blogs and social networks – and the multi-authored poetry collections that emerged and thrived in late seventeenth-century France.
Christophe Schuwey
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Nomads and Vagabond Monks: From the Text to the Reader in 18th Century Inner Asia

open access: yesReligions, 2022
Buddhist Studies scholarship in general, and its (re)turn to the literary specifically, is overwhelmingly concerned with texts and authors. But what can this research into “Buddhist texts” and “Buddhist authors”, however robust, ever reliably tell us if ...
Matthew William King
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Do tablado às livrarias: edição e transmissão de textos teatrais no Rio de Janeiro da segunda metade do século XIX From the stage to the bookstores: theatrical texts' edition and diffusion in Rio Janeiro at the second half of the XIXth century

open access: yesVaria História, 2009
Neste artigo serão exploradas as relações entre texto e oralidade e entre edição e transmissão de textos teatrais com o objetivo de mostrar que o estudo da materialidade dos textos e suas modalidades de transmissão são essenciais para a compreensão das ...
Silvia Cristina Martins de Souza
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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