Results 61 to 70 of about 169,245,677 (221)

Letture di frontiera: lettori di libri italiani nei territori francofoni orientali

Laboratoire Italien
This study explores how Italian-language books circulated, were read, and were used across French-speaking regions of Western Europe from the late fifteenth to the early seventeenth century.
Chiara Lastraioli
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Tracking Familial History of Reading and Math Difficulties in Children's Academic Outcomes. [PDF]

Front Psychol, 2021
Nguyen TQ, Martinez-Lincoln A, Cutting LE.   +2 more
europepmc   +1 more source

Education through print

Revista Diálogo Educacional
This article aims to analyz the edition of the Primeiro Catecismo da Doutrina Cristã (First Catechism of Christian Doctrine) published by the Vozes publishing house in 1964 which presents significant alterations in relation to editions published in ...
Aline Marie De Simone, Ana Maria de Oliveira Galvão, Maria José Francisco de Souza   +2 more
doaj   +1 more source

The problem of writing in mass education

Utbildning & Demokrati, 2019
What makes writing difficult to teach and learn? Why has writing been subordinated to reading in the context of literacy education? If more and more people are now expected to do more and more writing (at work, at school, and in the civic and social ...
Deborah Brandt
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Działalność Brytyjskiego i Zagranicznego Towarzystwa Biblijnego na ziemiach polskich (1816–1992). Rekonesans badawczy [PDF]

Kwartalnik Historyczny
In 1816, the Polish branch of the British and Foreign Bible Society (BFBS) was established in Warsaw to distribute Catholic and Protestant Bibles in Polish.
Joanna Nalewajko-Kulikov
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Autobiographies of the semi-literate: writing and reading in the memoirs of two peasants between the 19th and 20th centuries

Bibliothecae.it
Il saggio mette a confronto due autobiografie nate in contesti rurali tra XIX e XX secolo, per indagare come la scrittura diventi strumento di emancipazione individuale e di costruzione dell’identità.
Lodovica Braida
doaj   +1 more source