Results 111 to 120 of about 729,452 (331)

SemiLT: A Multianchor Transfer Learning Method for Cross‐Modality Cell Label Annotation from scRNA‐seq to scATAC‐seq

open access: yesAdvanced Science, EarlyView.
A multianchor transfer learning method, SemiLT, enables accurate cell label annotation in sparse scATAC‐seq data by leveraging well‐annotated scRNA‐seq references. By addressing temporal discrepancies between modalities, SemiLT improves rare cell type identification and batch correction.
Zhitong Chen   +3 more
wiley   +1 more source

Yawkey Foundations 2010 Grants Report [PDF]

open access: yes, 2011
Contains mission statement, board chair and president's message; grantee profiles in the areas of health, education, and human services; 2010 grants list and highlights; grant guidelines; and list of board ...

core  

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

IMPACT: The Journal of the Center for Interdisciplinary Teaching and Learning. Volume 8, Issue 1, Winter 2019 [PDF]

open access: yes, 2019
IMPACT: The Journal of the Center for Interdisciplinary Teaching & Learning is a peer-reviewed, biannual online journal that publishes scholarly and creative non-fiction essays about the theory, practice and assessment of interdisciplinary education ...
Cage, Stephanie   +6 more
core  

Enhancing Spatial Transcriptomics via Spatially Constrained Matrix Decomposition with EDGES

open access: yesAdvanced Science, EarlyView.
Imaging‐based spatial transcriptomics technologies are currently limited by their restricted gene detection capacity and low measurement accuracy. Moreover, the insufficient integration of spatial context and single‐cell reference data poses a significant challenge for comprehensive data analysis.
Jinyue Zhao   +5 more
wiley   +1 more source

Graduate Catalog, 1980-1981 & 1981-1982 [PDF]

open access: yes, 1980
https://scholar.valpo.edu/gradcatalogs/1009/thumbnail ...
Valparaiso University
core   +2 more sources

Bio‐Inspired SA‐FA Bionic Dual Receptor Electronic Skin for Intelligent Gesture and Material Cognition Systems Enhanced by Static‐Dynamic Mutual Interaction

open access: yesAdvanced Science, EarlyView.
In this work, bionic dual receptor (BDR) e‐skin based on the iontronic and triboelectric effects is proposed, inspired by the slow‐adapting and fast‐adapting receptors. Motivated by intelligent software algorithms and high‐speed hardware circuits, the proposed intelligent autonomous material cognition system integrated with the EDB e‐skin can ...
Hao Li   +5 more
wiley   +1 more source

Foundation Funding for the Humanities: An Overview of Current and Historical Trends [PDF]

open access: yes, 2004
Foundation Funding for the Humanities: An Overview of Current and Historical Trends, finds that funding for fields such as art history, history and archeology, languages and linguistics, area studies, and the humanistic social sciences increased two and ...
Loren Renz, Steven Lawrence
core  

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

open access: yesAdvanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng   +4 more
wiley   +1 more source

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

open access: yesAdvanced Science, EarlyView.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu   +5 more
wiley   +1 more source

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