Results 131 to 140 of about 335,151 (252)

The Driburger Kreis – an Institution in German History of Science, Medicine, and Technology

Bendl T, Klein GM, Stöger A. Der Driburger Kreis – Eine Institution der deutschen Wissenschaftsgeschichte. NTM : Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin : Journal of the History of Science, Technology, and Medicine ...
Bendl, Torsten, Klein, Gina Maria, Stöger, Alexander   +2 more
core   +1 more source

Journals under threat: A joint response from history of science, technology and medicine editors. [PDF]

Med Hist, 2009
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Butylphthalide combined with tenecteplase in mild disabling acute ischaemic stroke in China (BENEFIT-2): study protocol for a multicentre, randomised, double-blind, active-controlled trial. [PDF]

BMJ Open
Tang Q, Wang L, Tang L, Wang D, Wang D, Li Y, Zhang X, Liu R, Wang S, Zeng Y, Shen M, Zhang L.   +11 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

One Clinical Picture, Two Clinical Entities: A Case Report and Literature Review of Neurofibromatosis and Hemochromatosis. [PDF]

Children (Basel)
Melit LE, Borka Balas R, Tripon F, Prisca RA, Toth T, Stangaciu A, Najjar K.   +6 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Development and Validation of a Novel Thrombosis Prediction Model for Adult Immune Thrombocytopenia (ITP-THROMBO)

Journal of Blood Medicine
Huiling Yan,1 Xing Hu,1 Lijun Zhu,1 Yuhan Jiang,2 Chen Luo,2 Mengya Lv,1 Yan Wang,3 Juan Tong,1 Changcheng Zheng1 1Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and ...
Yan H, Hu X, Zhu L, Jiang Y, Luo C, Lv M, Wang Y, Tong J, Zheng C   +8 more
doaj  

Colorectal Polyp Occurrence Associated With the ZMIZ1-AS1 rs704017 Variant and Hypertension Among Taiwan Biobank Participants. [PDF]

Cancer Med
Shiu BH, Huang HC, Nfor ON, Hsu SY, Liaw YP.   +4 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source