Results 141 to 150 of about 335,151 (252)

Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study

open access: yesInternational Journal of Women's Health
Rasheed Ibdah,1,* Mohammed Al-Nusair,1,* Raghad Abuhalimeh,2 Saad A Mahmoud,1 Bushra Laswi,1 Sukaina Rawashdeh,1 Ayman Hamoudeh,3 Khalid A Kheirallah4 1Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Jordan ...
Ibdah R   +7 more
doaj  

Association between A Body Shape Index with constipation and diarrhea: NHANES 2005 to 2010. [PDF]

open access: yesMedicine (Baltimore)
Wei C   +6 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Unusual Presentation of Extensive Visually Significant Pseudoexfoliative Deposits on an Intraocular Lens Implant in a Pseudophakic Eye: Insights and Implications

open access: yesClinical Optometry
Abdelwahab Aleshawi,1 Mohammad Ali Al Qudah,1 Hamad Alazmi,2 Ahmed Al Sharie,2 Haya Sufyan Elnagar Jnr,3 Hosni Alzoubi,1 Saad Almutairi,2 Seren Al Beiruti,1 Rami Al-Dwairi1 1Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine ...
Aleshawi A   +8 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Pulse pressure trajectories and diabetes risk: A gender-specific cohort study. [PDF]

open access: yesMedicine (Baltimore)
Huang L   +9 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

History and Anthropology of Medicine and Biology

open access: yes, 2009
This course explores recent historical and anthropological approaches to the study of life, in both medicine and biology. After grounding our conversation in accounts of natural history and medicine that predate the rise of biology as a discipline, we ...
Helmreich, Stefan, Jones, David
core  

Home - About - Disclaimer - Privacy