Results 291 to 300 of about 5,700,334 (377)

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Implantable Loop Recorder Identifies Sustained Ventricular Tachycardia in a Pediatric Patient Despite Negative EP Study: A Case Report. [PDF]

Case Rep Pediatr
Liu JY, Numan MT.
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Book Reviews : Films of fact: a history of science in documentary films and television

Med Hist, 2009
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Free thyroxine modifying the association of serum ferritin with gestational diabetes risk: A retrospective cohort study. [PDF]

Nutr J
Chen X, Wang Y, Qian X, Xu Q, Zhang M, Su Y, Huang Q, Zhou N, Zhou W.   +8 more
europepmc   +1 more source

Malnutrition increases the risk of atrial fibrillation. [PDF]

BMC Cardiovasc Disord
Huang M, Zhang S, Xu C, Li B, Lai Y, Zhan R, Guo Y, Ma Y, Liao X, Wu X, Zhuang X.   +10 more
europepmc   +1 more source

Efforts to evaluate translational science's impact on biomedicine and society should incorporate Science and Technology Studies (STS). [PDF]

J Clin Transl Sci
Molldrem S, Moses JD, Tumilty E, Swanson P, Farroni JS, Smith EMR.   +5 more
europepmc   +1 more source

Case Report: Multi-cancer early detection utilizing blood-based genomics: Single-institution case series of novel cancer screening. [PDF]

Front Oncol
Khare S, Burton JC, De Asis F, Mekonnen S, Stewart-McLellan MJ, Potts D, Howard TL, Nabavizadeh N.   +7 more
europepmc   +1 more source

Trauma exposure among individuals with mood disorders: a cross-sectional study at a tertiary psychiatric facility in Uganda. [PDF]

BMC Psychiatry
Abaatyo J, Alol E, Kaggwa MM.
europepmc   +1 more source