Results 81 to 90 of about 1,469,531 (356)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Historians of science and the “Sobel Effect” [PDF]

open access: yesJCOM: Journal of Science Communication, 2005
In 1995, journalist Dava Sobel’s Longitude caused an earthquake in the history of science community. The present article analyses how only recently historians of science have fully realized the novelty the book represented.
Govoni Paola
doaj  

Charon in the Intelvi Valley. The Gorge of Osteno

open access: yesAcque Sotterranee, 2017
Not available.
Francesco Luzzini
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Translating the “Exact” and “Positive” Sciences: Early Twentieth Century Reflections on the Past of the Sciences in India

open access: yesThe Journal of Transcultural Studies, 2015
Inductivist theories of science dominated the landscape of the philosophy of science in nineteenth century Europe. This paper explores their vocation in late nineteenth and early twentieth century India.
Dhruv Raina
doaj   +1 more source

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