Results 141 to 150 of about 1,889,906 (345)

Sjuttonhundratalets vetenskap – vad hände och vad händer?

open access: yesLychnos, 2008
This essay documents the historiography of 18th century Swedish science and its main organizers Johan Nordström and his successor as professor of history of science and ideas at Uppsala University Sten Lindroth, active within this discipline until 1979.
Gunnar Broberg
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

A Feminist History of Science: Carolyn Merchant and The Death of Nature

open access: yesEducación y Ciencia
This paper aims to contribute to existing bibliographical references on the history of science in the Brazilian context by presenting a new perspective, an example of historical pluralism.
Roberto Barbosa, Iohana Santarelli
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

How to combine close and distant reading within the history of science and ideas : Two examples from ongoing research

open access: yes, 2022
This text gives two examples of how research within the history of science and ideas can make use of digital methods through a combination of close and distant reading. The first case maps all churches and prayer chapels in the Diocese of Luleå to answer the question if a Bible belt exists in Norrland; what it (if there is one) looks like, what its ...
Drakman, Annelie, Gelfgren, Stefan
openaire   +2 more sources

Science and its demarcation in the light of the history of ideas. A short outline with apparent and real implications for 'appearance and reality' [PDF]

open access: yes, 2013
The idea of 'science' (scientia, science, Wissenschaft) changed dramatically in the course of history: While it was understood as an epistemologically privileged endeavor from antiquity to the 19th century, the status of science and its demarcation from other intellectual activities became more and more problematic in the course of the 20th century ...
openaire   +1 more source

The dialogue of civilizations in the Birth of Modern Science [PDF]

open access: yes, 2008
Bala shows that the European Renaissance, an era nearly always assumed to be a key turning point in the history of ideas and culture, cannot be understood as a moment in the history of science if one ignores the intellectual consequences of European ...
Deuraseh, Nurdeng
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

A “crisscrossing” historical analysis of four theories of the press [PDF]

open access: yes, 2017
Because 2016 was the 60th anniversary of the publication of Four Theories of the Press, it is time to reexplore how this book, labeled as “the bible of comparative media studies,” was born.
Rantanen, Terhi
core  

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