Letter regarding unravelling the genomic landscape of Canadian <i>Borrelia burgdorferi</i>: a comparison across global strains; Piot <i>et al</i>. Microbial Genomics 2026;12:001606. [PDF]
Ogden NH, Mechai S, Margos G, Feil EJ.
europepmc +1 more source
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source
Holocene man-occupied caves and transformed wetlands as facilitating factors for Leishmania infantum in South America. [PDF]
Ribeiro SP +11 more
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Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
Genomic Diversity of Avocado in the Morogoro Region and Southern Highlands of Tanzania. [PDF]
Cortés AJ, Hussein JM, Juma I.
europepmc +1 more source
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
Imported Furuncular Myiasis in a Non-Endemic Setting: Two Case Reports of <i>Dermatobia hominis</i> Infection in Romania and a Review of Reports from Southeast and Eastern Europe. [PDF]
D'Amico G +4 more
europepmc +1 more source
An Increase in Imported <i>Plasmodium vivax</i> Malaria in New York City: Clinical and Demographic Trends Following Recent Migration. [PDF]
Berto CG +12 more
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