RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu+19 more
wiley +1 more source
Probable chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids syndrome: management with corticosteroids and intravenous immunoglobulin-a case report. [PDF]
Encarnación JA+8 more
europepmc +1 more source
Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves+17 more
wiley +1 more source
Teresa Huguet-Termes, Jon Arrizabalaga and Harold J. Cook (eds), Health and Medicine in Hapsburg Spain: Agents, Practices, Representations, Medical History Supplement No. 29 (London: The Wellcome Trust Centre for the History of Medicine at UCL, 2009), pp. vi + 158, £35.00/€40.00/$60.00, hardback, ISBN: 978-0-85484-128-8. [PDF]
James S. Amelang
openalex +1 more source
Regional reconstruction of flash flood history in the Guadarrama range (Central System, Spain).
C. Rodríguez-Morata+7 more
semanticscholar +1 more source
Tuneable Hydrogel Porosity via Dynamic Tailoring of Spinodal Decomposition
The authors introduce a straightforward method for dynamically halting the phase separation of a gelatin methacryloyl and poly(vinyl alcohol) (GelMA‐PVA) polymer blend in the context of a biofabrication process based on dynamic interface printing (DIP).
Michael Halwes+8 more
wiley +1 more source
Treponema pallidum infection in asymptomatic persons: A puzzling scenario in the Canary Islands (Spain) (2001-2020). [PDF]
Pérez-Arellano JL+11 more
europepmc +1 more source
PRC1‐Mediated H2Aub Loop Formation and Function in Arabidopsis
In the Arabidopsis genome, H2Aub and H3K27me3 marks do not always co‐localize, and some regions are marked exclusively by H2Aub. By using Capture‐Hi‐C, it is found that H2Aub loops are preferentially established between two H2Aub enriched regions.
Lingxiao Luo+8 more
wiley +1 more source
Influence of Comprehensive Pre-Anaesthetic Assessment on ASA Classification and Surgical Cancellations in Dogs and Cats: A Retrospective Observational Study. [PDF]
Cañón Pérez A+6 more
europepmc +1 more source