Results 111 to 120 of about 3,716,054 (304)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Under the historian’s radar: Local water-supply practices in Nairobi, 1940-1980
Water Alternatives, 2020 By presenting oral history material from two informal settlements in Nairobi, Kenya, the article illustrates how inhabitants during the period 1940 to 1980 acquired and used water on a daily basis.
Jethron Ayumbah Akallah, Mikael Hård
doaj
Technology Push, Demand Pull And The Shaping Of Technological Paradigms - Patterns In The Development Of Computing Technology [PDF]
An assumption generally subscribed in evolutionary economics is thatnew technological paradigms arise from advances is science anddevelopments in technological knowledge.
Dolfsma, W.A., Ende, J.C.M. van den
core +1 more source
How do different student constituencies (not) learn the history and philosophy of their subject? Case studies from science, technology and medicine [PDF]
, 2002 [FIRST PARAGRAPH] Why should H.E. teachers concern themselves with how their students do or don’t learn? Much has been said recently about the alleged merits and demerits of ‘student-centred’ learning, especially on the extent to which student ...
Gooday, G.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Testing the spirit of the information age [PDF]
, 2001 Every age has a 'spirit," The Information Age seems to be a more extreme case than most eras, with the constant barrage of messages promising social and individual salvation.
Cox, RJ
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The epistemological and artistic relevance of Robert Fludd’s memory theatres
GalilæanaThis article explores the memory theatres in Robert Fludd’s major work Utriusque cosmi historia (History of both worlds), focusing in particular on their epistemological and artistic relevance.
Ute Frietsch
doaj +1 more source
A Critical Exploratory Analysis of Black Girls\u27 Achievement in 8th grade U.S. History [PDF]
, 2018 The purpose of this study was to utilize an ethnically homogeneous design to examine Black female student U.S. History content-specific knowledge. The study aims to elucidate the importance of single-group analyses as an alternative to between-group ...
Druery, Donna M +2 more
core +1 more source