Results 91 to 100 of about 3,893,985 (306)

A History of Musculoskeletal Medicine and Its Place and Progress in Undergraduate Medical Education. [PDF]

open access: yesMed Sci Educ, 2023
McNeill K   +5 more
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Avicena, príncipe de los médicos. Vida, obra y legado para la medicina contemporánea

open access: yesRevista Cubana de Medicina
La historia de la Medicina está directamente relacionada con el surgimiento del hombre. Desde los tiempos de Hipócrates, antes de nuestra era, cuando existía la incertidumbre de definirla como arte o ciencia, no hubo un médico que entregara tanto aporte ...
Jorge José Pérez Assef   +2 more
doaj  

From the history of preventive medicine

open access: yesMedičnì Perspektivi, 2016
From the history of preventive ...
R. V. Savyna
doaj   +1 more source

The history of aeronautical medicine in Venezuela [PDF]

open access: yes
The Aerial Medical Service of the Ministry of Transportation and Communications of Venezuela was created on June 1949, and later became the Department of Aeronautical Medicine.
Iriarte, D. R.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Clinical Pharmacology in the UK, c.1950-2000: Industry and Regulation [PDF]

open access: yes, 2008
Annotated and edited transcript of a Witness Seminar held on 25 September 2007. Introduction by Professor Parveen Kumar, Barts and the London School of Medicine and Dentistry, University of London.First published by the Wellcome Trust Centre for the ...
Reynolds, LA, Tansey, EM
core  

THE HISTORY OF DENTAL MEDICINE IN OSIJEK. [PDF]

open access: yesActa Clin Croat, 2022
Volarić N, Jakab J, Včev A.
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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