Results 111 to 120 of about 3,893,985 (306)

Tracing embodied knowledge in the history of science and medicine: expanding the role of film in historical research

open access: yesScience Museum Group Journal
Tracing bodily knowledge in medical histories is a challenging task for researchers. Sensory, material and affective details are hard to find in archival sources and hard to put into words.
Paul Craddock, Anna Harris
doaj   +1 more source

A History of Penicillin: The Miracle of Medicine [PDF]

open access: yes, 2017
Dr. Heather McCreaThe discovery of penicillin in 1928 was a breakthrough in the world of medicine. Bacterial diseases could now be treated rapidly and easily without the long, complex regimens prescribed by doctors before this time. Surprisingly, many in
Rogers, John P.
core  

Prunus mira Koehne in Sichuan, China: Recorded History as a Medicine and Food, Modern Applications, Distribution, and Ethnobotanical Investigations. [PDF]

open access: yesFront Pharmacol, 2022
Zhang J   +11 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

History of Medicine Schedule 2010-2011 [PDF]

open access: yes, 2010
William Osler (1849-1919): America’s Most Famous Physician (Robert E. Rakel) The Assassination of John F. Kennedy: A Neurosurgeon’s Eyewitness Account of the Medical Aspect of the Events of November 22, 1963 (Robert G.
Houston History of Medicine Society
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Foot and Mouth Disease: The 1967 outbreak and its aftermath [PDF]

open access: yes, 2003
The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 11 December 2001. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2003.
Reynolds, LA, Tansey, EM
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Prof. Dr. Bedđ N Sehsuvaroglu (1914-1977) , A famous turkish historian of medicine and pharmacy and eczacilik tarđhđ derslerđ (lectures on the history of pharmacy), his book [PDF]

open access: yes, 2007
Reason for this study is to study an important book of Sehsuvaroğlu , a famous Turkish historian of medicine and pharmacy from the point of history of medicine and pharmacy.As method , Sehsuvaroğlu’s biography is given as chronological and his book’s ...
Erdemir, Ayşegül Demirhan   +1 more
core  

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